Prevention of retinopathy of prematurity

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Prevention of retinopathy of prematurity.

Retinopathy of prematurity (ROP) is related to oxygen-regulated vascular endothelial growth factor and to insulin-like growth factor-I. After premature birth, supplemental oxygen induces a retinal hyperoxic condition with vasoconstriction and to a definitive interruption of retinal vasculogenesis. Peripheral ischemia may stimulate retinal neovascularization and the onset of additional ROP-relat...

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Retinopathy of prematurity: the need for prevention

More than 450,000 babies are born prematurely in the USA every year. The improved survival of even the most vulnerable low body weight preterm infants has, despite improving health outcomes, led to the resurgence in preterm complications including one of the major causes for blindness in children, retinopathy of prematurity (ROP). The current mainstay in ROP therapy is laser photocoagulation an...

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A Paradigm Shift in the Prevention of Retinopathy of Prematurity

For more than 50 years it has been known that oxygen therapy can lead to retinopathy of prematurity (ROP). Recent clinical research has led many neonatologists to lower the target oxygen saturation alarm limits to 85–93% and to titrate the inspired oxygen in small increments. Despite efforts to optimize oxygen therapy, the number of cases of severe ROP remains high as more extremely low birth w...

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A paradigm shift in the prevention of retinopathy of prematurity.

For more than 50 years it has been known that oxygen therapy can lead to retinopathy of prematurity (ROP). Recent clinical research has led many neonatologists to lower the target oxygen saturation alarm limits to 85-93% and to titrate the inspired oxygen in small increments. Despite efforts to optimize oxygen therapy, the number of cases of severe ROP remains high as more extremely low birth w...

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editorial: retinopathy of prematurity

it has been estimated that each year 50,000 newborns born prematurely and underweight and are candidates to have retinopathy of prematurity (rop) .1 in the developing countries where we see most of the blind children, rop is accused to be one of the essential causes of blindness.2 rop and its consequences (impaired vision and blindness) could be prevented in most cases by an early ocular examin...

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ژورنال

عنوان ژورنال: Arquivos Brasileiros de Oftalmologia

سال: 2011

ISSN: 0004-2749

DOI: 10.1590/s0004-27492011000300016